Cutaneous granulomas in children with combined immunodeficiency
Identifieur interne : 002F80 ( Main/Exploration ); précédent : 002F79; suivant : 002F81Cutaneous granulomas in children with combined immunodeficiency
Auteurs : Elaine C. Siegfried ; Neil S. Prose ; Noah J. Friedman ; Amy S. Paller [États-Unis]Source :
- Journal of the American Academy of Dermatology [ 0190-9622 ] ; 1991.
English descriptors
- Teeft :
- Acad dermatol, Acral distribution, Acral lesions, Acrolocated syndrome, American academy, Biopsy, Biopsy material, Biopsy specimens, Careful consideration, Chronic granulomatous disease, Cutaneous, Cutaneous granulomas, Dermatology, Erythematous papules, Fungal infection, Granuloma, Granuloma annulare, Granuloma formation, Granulomatous, Granulomatous dermatitis, Humoral immunodeficiency, Immunocompromised patient, Immunodeficiency, Immunodeficiency disorders, Infectious causes, Iowa city, Lesion, Lymphocyte, Noninfectious granulomas, Recurrent otitis media, Sarcoidlike granulomas, Sarcoidosis, Skin lesions, Slight healing, Special stains, Syndrome, Systemic corticosteroids, Thorough history, Transaminase levels, Visceral granulomas.
Abstract
Noninfectious cutaneous granulomas, particularly in an acral distribution, may be an early sign of mixed cellular and humoral immunodeficiency. Special stains of skin biopsy sections and cultures for bacteria, acid-fast bacilli, and fungi are important in eliminating the possibility of underlying pathogens. In three children with combined immunodeficiency and cutaneous granulomas, the administration of moderate- to high-dose systemic corticosteroids was the most effective therapy. However, careful consideration should be given before administering systemic corticosteroids to an immunocompromised patient.
Url:
DOI: 10.1016/S0190-9622(08)80965-6
Affiliations:
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Le document en format XML
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Special stains of skin biopsy sections and cultures for bacteria, acid-fast bacilli, and fungi are important in eliminating the possibility of underlying pathogens. In three children with combined immunodeficiency and cutaneous granulomas, the administration of moderate- to high-dose systemic corticosteroids was the most effective therapy. However, careful consideration should be given before administering systemic corticosteroids to an immunocompromised patient.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Illinois</li></region><settlement><li>Chicago</li></settlement></list><tree><noCountry><name sortKey="Friedman, Noah J" sort="Friedman, Noah J" uniqKey="Friedman N" first="Noah J." last="Friedman">Noah J. Friedman</name><name sortKey="Prose, Neil S" sort="Prose, Neil S" uniqKey="Prose N" first="Neil S." last="Prose">Neil S. 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